1 Differentiation of Neurons Restricts Arbovirus Replication and Increases 1 Expression of the Alpha Isoform of IRF - 7 2 3
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چکیده
Differentiation of Neurons Restricts Arbovirus Replication and Increases 1 Expression of the Alpha Isoform of IRF-7 2 3 Kimberly L. W. Schultz, Patty S. Vernon, and Diane E. Griffin 4 5 W. Harry Feinstone Department of Molecular Microbiology and Immunology, Johns 6 Hopkins Bloomberg School of Public Health, Baltimore, MD 21205 7 8 Running title: Antiviral priming of differentiated neurons 9 10 Present address: Scripps Mercy Hospital, San Diego, CA 11 12
منابع مشابه
Differentiation of neurons restricts Arbovirus replication and increases expression of the alpha isoform of IRF-7.
UNLABELLED Susceptibility to alphavirus infection is age dependent, and host maturation is associated with decreased virus replication and less severe encephalitis. To identify factors associated with maturation-dependent restriction of virus replication, we studied AP-7 rat olfactory bulb neuronal cells, which can differentiate in vitro. Differentiation was associated with a 150- to 1,000-fold...
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تاریخ انتشار 2014